The PARCC is dedicated to experimental disease-oriented research and has as primary aim to catalyze and speed up the production of basic knowledge related to the understanding of the cellular and molecular basis of cardiovascular disease. Its main mission is to maintain an optimal scientific and medical environment in order to promote excellence in cardiovascular translational research.
Our overall goals for the 2014-2018 period are :
1. to pursue internationally leading laboratory-to-bedside research programs that address fundamental molecular, cellular and physiological mechanisms underlying normal and abnormal cardiovascular function and diseases ;
2. to maintain a highly collaborative, multi-disciplinary environment which catalyzes the pursuit of imaginative and innovative research programs, based on complementary expertise of the PARCC teams (cell and molecular biology, physiology/pathophysiology, pharmacology, immunology, endocrinology, genetics, epidemiology, imaging) ;
3. to link these to translational research that improves the prevention, diagnosis and treatment of human cardiovascular disease ;
4. to establish an optimal environment with cutting-edge technology; 5. to undertake high-quality research training of non-clinical and clinical scientists.
The strategy to achieve our objectives is multifaceted, but is mainly built upon the expertise in basic and clinical translational research of the teams that started internal collaborations, as well as upon strong interactions with the clinical divisions at HEGP (cardiology, cardiovascular prevention, hypertension, medicine, genetics, cardiac and vascular surgery), as well as with the Clinical Investigation Center and the Clinical Research Unit.
MAIN ORGANIZATIONAL PRINCIPLES
The organization of the research structure and its environment crucially influence the creation of fundamental new knowledge. It is therefore of utmost importance that the PARCC recruit high quality teams involved in cardiovascular research, working in synergy with clinical laboratories and departments to bolster the translation to clinical applications. The PARCC (4,200 m2) houses 14 research groups. hospital.
Teams hosted at the PARCC have a long- Such a research structure brings together a critical standing experience of initiating and conducting clinical mass of basic and clinical scientists necessary to make studies in direct coordination with clinicians. major breakthroughs in cardiovascular biology and medicine.
Gathering cardiovascular scientists with complementary expertise (cell and molecular biology, physiology/pathophysiology, pharmacology, genetics, epidemiology) creates an environment with a degree of scientific integration that are optimal for scientific breakthroughs to occur, through intense and frequent interactions between scientists. Under these principles, the PARCC is hosting excellent research teams with a broad spectrum of expertise in cardiovascular research, and implementing cutting- edge technology to facilitate basic and disease-oriented research.
The PARCC aims to play a major role in the promotion and development of cardiovascular research in the Région Ile-de-France, through links with the CORDDIM (Domaine d’Intérêt Majeur “Cardiovasculaire – Obésité – Rein – Diabète”).
The PARCC is inserted within the International and European space of research through links of its research teams with EU funded European Networks and Transatlantic Leducq Foundation Networks. In addition, it acts to develop formal links with international academic institutions.
Clinical research is conducted in coordination with the Clinical Investigation Center (CIC) at HEGP (director: Pr. Michel Azizi).