Loschmidt Laboratories

We are Loschmidt Laboratories based at the Masaryk University and the International Clinical Research Center of St. Anne’s University Hospital Brno. Our laboratories are located at the University Campus Bohunice in Brno, Czech Republic.

Proteins are natural building blocks of all living organisms and participate in virtually every process within cells. Many natural proteins are enzymes that catalyse biochemical reactions and are essential for metabolism. Proteins can be found everywhere — they play a role in the development of medicines, in food and beverages processing, animal nutrition, textiles, household cleaning, fuels and energy generation. And therefore the study of proteins is valuable for the whole society.

We conduct interdisciplinary research in the field of protein engineering. We wish to understand the structure-function relationships of proteins and improve their functionalities for biotechnologies. We study mechanisms of Alzheimer’s disease and develop novel drugs for acute stroke. Our goal is to be recognised as one of the leading protein engineering groups in Europe. We will consistently strive to publish our findings in reputable scientific journals, to develop software tools and lab-on-chips, and transfer results to practice.

The key components of our daily activities include collaboration between experimentalists and theoreticians, solidarity among the laboratory team, and mentoring of young colleagues — all while maintaining a friendly and creative working environment to honour the name of Jan Josef Loschmidt.