PhD in pathophysiology of systemic metabolic diseases

Offer Description

The laboratory of hepato-gastroenterology is offering a 4 year-PhD fellowship to study the skeletal muscle to liver axis in driving metabolic dysfunction associated liver disease (MAFLD). We demonstrated profound structural and metabolic changes in the muscle compartment in preclinical models as well as in patients with MAFLD. The project aims at investigating how the altered muscle triggers immune modulations and how such immune changes are permissive for the progression of liver disease, including in animals subjected to a physical exercise program. It also implies the development of new methodologies for in vivo diagnosis of organ inflammation (in collaboration with industry). The research subject is currently a hot topic in diseases associated with obesity such as MAFLD/NASH and diabetes, but in many other chronic diseases as well.

Requirements

Research Field Medical sciences » Health sciences

Education Level Master Degree or equivalent

Additional Information

Work Location(s)

Number of offers available 1

Company/Institute UCLouvain / Institute for Experimental and Clinical Research

Country Belgium

City Brussels

Postal Code 1200

Street avenue Emmanuel Mounier 52, Box B1.52.01

Where to apply

E-mail isabelle.leclercq@uclouvain.be

Contact

City Brussels

Website https://uclouvain.be/fr/index.html

Street avenue Emmanuel Mounier 52, Box B1.52.01

Postal Code 1200

E-Mail isabelle.leclercq@uclouvain.be