PostDoc (f/m/d) – tumor microenvironment in pediatric cancer

Are you looking to put your experimental and bioinformatic skills to the test?
Are you fascinated by cancer biology and using multi-omics data to devise new treatment avenues?
Then this project is for you!

For a recently funded Excellence Program (www.fwf.ac.at/en/research-radar/10.55776/EFP45) we are looking for an interdisciplinary Postdoc (f/m/d) to unravel the role of T cells in the tumor microenvironment of osteosarcoma, a devastating pediatric cancer. In this role, you will work in a leading center for pediatric oncology. The Taschner-Mandl Lab tackles unresolved questions of pathogenesis of cancer in children (Fetahu IS, Nat Comms, 2023). You will work at the intersection of cancer genomics and tumor immunology, employ single cell- and spatial omics techniques, with the final goal to develop innovative cellular therapies against osteosarcoma.

Your responsibilities

You will:

• Handle primary tissue and cell cultures for genomic, spatial imaging and functional studies
• Analyze genomics data (*-seq) and identify clinically relevant biological signals
• Contribute to an excellence research program with a clear and important mission
• Work as part of a dynamic and multi-disciplinary research team and benefit from joint supervision by computational and cancer experts
• Write manuscripts, present at scientific conferences, and attend courses
• Apply for PostDoc fellowships and learn how to obtain funding for your research
• Supervise and support junior members of our team

Your profile

What you bring for this position:

• PhD degree (obtained or in final stages) in the areas of cancer genomics or immunology
• At least one first-author paper in a peer-reviewed journal
• Proficiency in lab experimental work including primary tissue and cell culture, NGS library preparation, genome editing, knockdown/overexpression, microscopy and tissue/spatial multi-plex imaging/omics, etc.
• Proficiency in NGS data analysis (R and python) is an asset
• Self-initiative and proactive mind-set
• Experience in single cell RNA-seq analysis or tissue imaging technologies are a plus

Our offer

Does this sound interesting? This is our offer to you:

• A challenging role in a meaningful, inspiring, and international environment
• An outstanding working atmosphere in young and dynamic team funded by a highly prestigious EXCELLENCE program
• Access to state-of-the-art infrastructure
• Flexible working hours, discounted lunch and other great benefits
• Great location in the center of Vienna, a capital of biomedical research in Europe with excellent quality of life
• An attractive salary package according to the Austrian Science Fund FWF (https://www.fwf.ac.at/en/research-funding/personnel-costs/)

Who we are

The St. Anna Children’s Cancer Research Institute (St. Anna CCRI), located in the center of Vienna, the most livable city in the world and one of the most important sites for biomedical research in Europe. St. Anna CCRI is a multidisciplinary and internationally networked center of excellence whose goal is to contribute to a sustainable improvement in the cure rates of childhood and adolescent cancers through innovative research and development. Due to the close cooperation between clinic and research, St. Anna CCRI offers the ideal environment for cutting-edge research at a high international level and its implementation in clinical practice. and its translation into clinical practice.

St. Anna CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment of mutual respect to everyone without regard to race, colour, religion, national origin, age, gender identity or expression, disability, or any other characteristic protected by applicable laws, regulations and ordinances.

Find more information here: https://ccri.at/

Your application

We are looking forward to your application! Applications should at least contain your Curriculum Vitae, a cover letter, list of publications (please mark / explain your three top contributions), and the contact details of three references.

The application deadline is the 30.11.2024. Applications will be reviewed on a rolling basis until the position is filled.