Do you want to start your new lab at one of Karolinska Institutet’s leading departments?

We seek inspiring, creative candidates that want to start their careers as independent researchers at the department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet. We are one of the largest departments at Karolinska Institutet, focused on basic research in biomedical sciences. We have a long and proud history of ground-breaking science, particularly developing innovative methods and applying them to understand fundamental human biology and the mechanisms that cause disease.

MBB is located in the beautiful new Biomedicum research center, along with four other departments. You will join a vibrant community of more than a thousand researchers, with outstanding facilities and a wide range of talents. Biomedicum is situated close both to the Karolinska University Hospital (for clinical collaborations) and the Science for Life Laboratory, a national research infrastructure of unique technologies.

This is who you are

We seek candidates who dream big, aim high and want to solve important and fundamental biomedical problems. You should be open to new ideas and collaborations, responsive to the ideas of others, and willing to develop and test your skills in a team environment.

The employment as Assistant Professor is time limited for 6 years with the right to apply for promotion to Senior Lecturer.

What do we offer?

If you have an outstanding proposal, we are ready to support you with a generous startup package, including six years employment as assistant professor and 13 MSEK unconditional research funding to cover your salary, rent, and any other research costs. the Department and KI will also provide support in the preparation of applications to Swedish and International grants such as ERC and KAW (Knut and Alice Wallenberg Foundation). We recognize the significance of supporting our researchers and their families. At our department, we appreciate the vital role that partners and families play in the lives of our scientists. Information about moving to Sweden can be found here https://staff.ki.se/international-staff and here https://www.sdcn.se/

The department has broad interest and all areas of preclinical biomedical research are eligible, for example:

Fundamental human biology and disease

• Mechanisms of transcriptional and translational gene regulation.
• Mechanistic roles for intermediary metabolism in mammalian physiology and pathology.
• Understanding molecular mechanisms in redox control of cellular functions.
• Biological effects of stable isotopes
• Neuroimmunology
• Brain disease, including multiple sclerosis, schizophrenia, neurodegenerative disease, brain cancer
• Cancer

Technology

• Cryo-electron microscopy methods development and structural biology (300kV cold-FEG Krios
• microscope available)
• Ultra-high resolution light microscopy techniques (MINFLUX available)
• Linking imaging modalities, and linking imaging to omics
• Engineering of nucleic acid- or protein-based systems
• Protein design
• Precision cell or tissue engineering, e.g. CRISPR/Cas9-based (epi)genome editing, human
• organoids, cell printing
• Nucleic acid-based nanomedicines, delivery mechanisms, programmable drugs
• Methods development for high-throughput single-cell and spatial analysis of modalities as chromatin, RNA and protein, among others.
• Development of assays for clinical diagnostic

About KI

A creative, international and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement

Eligibility requirements

Those eligible for employment as an Assistant Professor are individuals who have been awarded a PhD or attained equivalent research competence. Preference should be given to those who were awarded a PhD or attained equivalent research competence no more than five years prior to the expiry of the application period for the position as assistant professor, but excellent applicants who have completed their PhD more than five years ago are also welcome to apply.

Location: Solna

Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents:

• CV (up to 3 pages) including contact information to two references, preferably previous supervisors, and description of their professional relationship to the applicant. Clearly state the PhD date. Clearly state the names of all previous supervisors (PhD supervisor, post-doc supervisor(s)).
• List of 5 most relevant original (not reviews, corresponding- or views- pieces) publications for the application in exactly this format: Full title, year, Journal, All authors listed in the original published order with the applicant's name in bold and the PhD and/or Post-doc supervisors names underlined (when they are on the papers). Mark shared authorships. – Changes to the author order or similar will disqualify the application.
• Research plan (up to 5 pages, excluding references)
• A PDF of your single most important paper or preprint

Welcome to apply at the latest 2024-09-13

The application is to be submitted through the Varbi recruitment system

Want to make a difference? Join us and contribute to better health for all

1. Professor Björn Högberg , bjorn.hogberg@ki.se

1. Anurupa Nagchowdhury (OFR), anurupa.nagchowdhury@ki.se