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Université de Strasbourg
Post-doc in Single-Cell Molecular Biology & Microfluidics
Université de Strasbourg
Depuis le premier janvier 2009, l'Université de Strasbourg est une réalité. Cette création est le fruit d'un long travail et de l'implication de tous.
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Publié: il y a 26 jours
Date limite d'inscription: Non Spécifiée
Localisation: Strasbourg, France
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Post-doc in Single-Cell Molecular Biology & Microfluidics

Architecture and Reactivity of RNA; Team “Digital Biology of RNA”

Institut de Biologie Moléculaire et Cellulaire

Strasbourg-France

http://www-ibmc.u-strasbg.fr/spip-arn/spip.php?rubrique134&lang=en

A post-doc position (18 to 24 months) will be available starting from October 1st 2018 in the team “Digital Biology of RNA” headed by Michael Ryckelynck in IBMC (Strasbourg-France). The team is specialized in the development and the use of droplet-based microfluidics to address biological questions related to the study of gene expression regulation, especially those involving non-coding RNAs.

In this context, we are seeking a highly motivated post-doc to be part of a project aiming at exploiting a new microfluidic-assisted technology recently developed by the team to monitor gene expression and further extend it to the analysis of RNAs while operating at a single-cell resolution. Activities will include molecular biology, purification of biological molecules, droplet-based microfluidics and sequence analysis.

Required knowledge and skills:

  • Expertise in molecular biology especially in the manipulation of nucleic acids (e.g. preparation of NGS libraries)
  • Prior experience with microfluidics, basic knowledge in Bioinformatics (e.g. using Python to handle sequencing data) would be appreciated
  • Prior experience in microbiology and/or mammalian cell culture would be appreciated
  • Proven track record to work efficiently, both independently and as part of a team
  • Written and oral communication skill as well as fluency in English.

The recruited person will have to conduct a research combining molecular biology and microfluidics and aiming at characterizing sub-classes of RNAs in high-throughput regimes and with single-cell resolution. Reaching these goals will require the candidate to have a strong expertise in molecular biology as well as the capacity to work at the interface of biology, microfluidics, chemistry and bioinformatics. In particular, the candidate will have to interact with the other researchers of the team (as well as collaborators) and valorize the data by writing articles on the topics.

Applications (CV, list of publications and 2 references) should be sent to Michael Ryckelynck (m.ryckelynck@unistra.fr).

Keywords: microfluidics, molecular biology, microbiology, gene expression

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