Votre alerte-emploi vient d’être créée avec succès.
Inserm
Postdoctoral position available in the “Nods-like receptors in infection and immunity” Group at the Institut Pasteur de Lille
Inserm
L'Inserm s’est vu confier, en 2008, la responsabilité d’assurer la coordination stratégique, scientifique et opérationnelle de la recherche biomédicale.
Visitez la page de l'employeur
DÉTAILS DE L'OFFRE
Publié: il y a 1 an
Date limite d'inscription: Non Spécifiée
Localisation: Paris, France
Vous devez vous connecter ou créer un compte pour enregistrer cette offre
Veuillez mentionner que vous avez trouvé ce poste sur Academic Positions lors de votre candidature.
PARTAGER CE POSTE

Postdoctoral position available in the “Nods-like receptors in infection and immunity” Group at the Institut Pasteur de Lille

logos-uni

A funded postdoctoral position is available in the “Nods-like receptors in infection and immunity of Lille” Unit headed by Mathias Chamaillard for studying how the T follicular helper cell commitment is influenced by the oscillatory behavior of the gut microbiota and how circadian activity of the gut microbiome is regulated by CD4 T cells over the course of a day. The Chamaillard's laboratory at the Institut Pasteur de Lille is interested in defining how deregulation of several Nods-like receptors break down in colitis-associated colorectal cancer. Using a variety of techniques and complex genetic models, we have contributed to the field of mucosal immunology by identifying novel dendritic cell subsets and several pathways that underlie inflammation-driven carcinogenesis (Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9601-6, J Clin Invest. 2013 Feb;123(2):700-11 and Mucosal Immunol. 2017 Nov 15. doi: 10.1038/mi.2017.87).

Project Outline: The International Agency for Research on Cancer classified shift work with chronodisruption as an exposure circumstance that poses a carcinogenic risk. The circadian clock is an endogenous time-tracking system that allows most living organisms to anticipate and adapt to several environmental changes. In this context, we seek to obtain a mechanistic understanding on the interplay between the circadian activity of the gut microbiome and CD4 T cells. Thanks to excellent facilities at the Institut Pasteur de Lille and to strong collaborations with the Institute Pasteur of Paris and the inflammation research center from the VIB in Ghent, state-of-the-art technologies are available including those combining imaging and flow cytometry. The scientific outputs of our multidisciplinary approach has a direct clinical perspective that will have a broad impact on the development of chronomodulated drugs as exemplified by the strong of interest of stakeholders and biotech companies on the gut microbiota in oncology. Upon completion of the project, we will look for collaboration with industrial partners involved in microbiota-derived molecule development and next generation probiotics development in order to favor public-private partnership either locally or internationally for transfering our results from bench to bedside through clinical trial.

Candidate requirements: The applicants of any nationality must hold a PhD and/or a MD degree and should be highly motivated and ambitious. The applicants should have a strong background in bone marrow chimera experiments, cell cytometry and cellular imaging with a strong interest on oncology and mucosal immunology. Technical expertise in flow cytometry will be of advantage. Fluent knowledge of English and excellent communication skills are expected. Interested candidates are encouraged to submit a motivation letter describing their background, a CV and two references letters to mathias.chamaillard@inserm.fr.

Expected employment starting date: 2018-06-01.

Lire la suite
Candidatez ici
Vous devez vous connecter ou créer un compte pour enregistrer cette offre

POSTULER

Détails personnels
Upload your CV and attachments
Le format de fichier doit être .doc, .pdf, ou .rtf et le fichier ne peut pas dépasser 2 Mo au total.
Le format de fichier doit être .doc, .pdf, ou .rtf et le fichier ne peut pas dépasser 2 Mo au total.

En déposant une candidature pour un poste publié sur Academic Positions, vous acceptez nos conditions générales et notre politique de confidentialité.

S'ABONNER A DES ANNONCES COMME CELLES-CI

2 POSTES PROPOSÉS PAR CET EMPLOYEUR

Inserm
Inserm
Localisation: Montigny-le-Bretonneux, France
Two Years Postdoctoral Position in Virology
A 2 years postdoctoral research position is available starting during the first semester of 2019 to study respiratory syncytial virus multiplication in the virology group at the research unit U1173 (INSERM – Université de Versailles saint Quentin en Yvelines). This young...
Inserm
Inserm
Localisation: Nice, France
Postdoctoral Research Associate in Neural and Cancer Biology in the French Institute of Health and Medical Research, Nice, France
An exciting three-year postdoctoral position is immediately available in the French National Institute for Health and Biomedical Research (INSERM; https://www.inserm.fr/en), at the Mediterranean Center of Molecular Medicine, located in Nice, France. The center fosters a dynamic...

OFFRES D'EMPLOI SIMILAIRES

Postdoctoral Positions
Aix-Marseille Université
Publié il y a 6 jours
Two Years Postdoctoral Position in Virology
Inserm
Publié il y a 1 mois
Engineer/ Post-doctoral position
Institut Curie
Publié il y a 3 mois
Postdoctoral Position in Microfluidics, Cybergenetics and Synthetic Biology
Université Paris Diderot
Publié il y a 3 mois

CAREER ADVICE

[[excerpt]]

By [[ author ]]
Posted [[ publishingDate ]]

[[title]] ([[ nbHits ]])

[[title]] ([[ nbHits ]])

[[title]] ([[ nbHits ]])

No results found for

Search tip

  • Check for spelling mistakes
  • Reduce the number of keywords used or try using a broader search phrase

[[title]] ([[ nbHits ]])

[[title]] ([[ nbHits ]])

[[ name ]]
[[ name ]]
[[ excerpt ]]
[[ city ]], [[ region ]] [[ availableJobsBlock ]]
Featured Featured employer
Short list
Développer la liste
[[title]]
[[ employerName ]]
[[ employerName ]]
[[ favoriteBtnText ]]
Vous devez vous connecter ou créer un compte pour enregistrer cette offre
[[ locationCity ]], [[ locationCountry ]]  ·  Publié [[ publishingDateTimestamp ]]  ·  [[ applicationDeadlineDateTimestamp ]]
[[ title ]]
Publié [[ publishingDateTimestamp ]] [[ applicationDeadlineDateTimestamp ]]