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A*Midex
Post-Doc position in synthesis chemistry of oligonucleotides an/or nanoformulations
A*Midex
La mission de la Fondation est de gérer les fonds alloués au titre du projet A*MIDEX.
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Publié: il y a 1 an
Date limite d'inscription: Non Spécifiée
Localisation: Marseille Cedex 07, France
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Post-Doc position in synthesis chemistry of oligonucleotides an/or nanoformulations

Post-Doc position in synthesis chemistry of oligonucleotides an/or nanoformulations available at the Center for Cancer Research of Marseille (CRCM) in the Prostate Cancer Group. The position is based at Institut Paoli Calmettes Institute (IPC) campus and funded by Aix-Marseille University Excellence Initiative for 24 months, with possible options for renewable and/or future recruitment by Inserm and CNRS. The salary is dependent on the candidate’s experience.

The selected candidate will be responsible to carrying experiments to develop a novel nucleolipids-based nanocarrier functionalized with targeting moieties (PMSA) for co-delivering radionuclides and antisense oligonucleotide against Hsp27 (OGX-427) in order to improve anti-tumor effects molecular radiotherapy in PCa. The experiments will be carried out in the molecular oncology team of the CRCM, in the biopathology department of IPC, and in the European Center for Research in Medical Imaging (CERIMED).

Candidates should be very motivated and have expertise in synthesis chemistry of oligonucleotides an/or nanoformulations.

The selected candidate will be responsible to develop pre-clinical evaluation of using nanovectorized antisens in castrate-resistant prostate cancer models in order to licence 3 related international patents with industrial partner. The selected candidate will manage master and PhD students that will work on the project. This work is done in collaboration with Pr. Philippe Barthelemy (ChemBioMed, INSERM U869, Bordeaux) and is funded by Aix-Marseille University Excellence Initiative.

Expected start date: April 2018.

Please send a CV with the name of 3 referees and a motivation letter containing a summary of your current research and your scientific interests to palma.rocchi@inserm.fr and david.taieb@ap-hm.fr.

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