Post-doc offer in Computer Science applied to biomedical imaging
The successful applicant will join the collaborative project L-iOS (ANR PRCE 2016) aiming at developing a portable and highly accurate (spatially and spectrally) light sensor array for medical applications. He/she will join DiMABio group at Institut Fresnel and will develop and optimize a Monte Carlo simulator to model light propagation through biological tissues in the visible to mid-infrared (500-1500 nm). In this wavelength range, tissues are modeled as highly absorbing and scattering media. The light propagation phenomenon can be described by the Radiative Transfert Equation. One of the most versatile ways of solving this integro-differential equation is by Monte Carlo simulations. This forward model will be introduced in an inverse problem resolution loop in order to reconstruct the 3D maps of the parameters of interest, such as absorption or reduced scattering coefficients, and, in fine, concentrations of the biomarkers of interest (oxy- and deoxy-hemoglobin, glucose, fat…).
Faculty Positions All Ranks
emlyon business school invites applications for faculty positions at all ranks for its European campuses (Paris / Lyon / Saint-Etienne). Successful candidates are expected to…
Postdoctoral position in Bioinformatics
Extracellular stimuli are perceived by cells and converted into signaling cascades relayed by dynamic phosphorylations of proteins. These cascades finally reach the chromatin, made up of histones and DNA, and impact it, in part by changing the modification pattern of its histone constituents. Ultimately, the gene expression program is revisited, to allow the cells to develop an adequate response to the stimulus. We wish to decipher these iterative steps upon uptake by endothelial cells of extracellular vesicles produced by cancer cells: these vesicles contain microRNAs and proteins, including oncogenes, which can have combined impacts on the recipient cells. The obtained data should allow better understanding how cancer tumors manipulate their environment to ensure their survival, in particular by stimulating angiogenesis.
Grenoble Quantum Engineering - PhD Program 2017
The Grenoble Quantum Engineering (GreQue) doctoral programme is supported by the European Union, via a COFUND Marie Slodowska Curie Action. It will provide the laureates with a…
Post-doctoral position in bioorganic chemistry
The development of selective probes and drugs to detect and disturb nucleic acid related processes is of importance to fundamental biology, clinical diagnostics and therapeutics. In the past decade, there has been growing evidence that the formation of unusual nucleic acid structures, such as G-quadruplexes (G4), profoundly influences cell regulation. Those motifs are suspected to form in key regulatory regions of human cells and their occurrences in human and pathogens have been compellingly associated with diseases such as cancers, viral infections and degenerative disorders. Through an interdisciplinary program, at the crossroads of synthetic chemistry, combinatorial chemistry, molecular biology and biophysical organic chemistry, we ambition to design, synthesize and exploit molecular ligands with the ability to specifically recognize and affect distinct G4 structures of biological interest.